CHAPS

APPLICATIONS

-Zwitterionic detergent.

-Non-denaturing.

-Electrically neutral.

-Has all the advantages of sulfobetaine containing detergents: hydrophobic, bile salt, and anionic detergents in a single molecule.

-Better at solubilizing proteins and breaking protein-protein interactions.

-Less protein aggregation than non-ionic detergents.

-Capable of solubilizing opiate receptors.

-CHAPS can be removed from protein solutions with a detergent removing gel or by dialysis.